Chemistry Reference
In-Depth Information
detect sweat formation, but it also needs to detect how much. Therefore,
the conditions for performing this experiment must be well identified
in order to obtain reproducible results, and this matter is still under
investigation.
Preliminary results (Fig. 10.8) showed that there is a clear difference in
the slope of the decrease of the resistance, and the resistance value after
the first strong declining part of the curve is much smaller for the cystic
fibrosis patient (up to now, there is only one curve of a positive cystic fibro-
sis patient). From curve 2, which is recorded from a cystic fibrosis patient,
and the other curves (1), which are recorded from healthy people, it can be
seen that a clear systematic difference is obtained, even though an error
margin of more than 50% was allowed for the curves obtained from healthy
people. This can be explained by the much higher electrolyte concentration
in the sweat of the cystic fibrosis patient. First the slope is higher because,
for an equal sweat-formation rate, more electrolyte is excreted by the cystic
fibrosis patient and, due to this same effect, the concentration of the elec-
trolyte in the sweat formed during a certain and preset time is higher, thus
giving rise to a lower electrolyte cell resistance.
10.6
References
1. http://www.muco.be/illnes/nl/index_1.html.
2. Stern M., Picard C., Grevet D.,
Presse Med
,
31
(2002) 263-270.
3. Feigelson J., Pecau Y.,
Sem de Hopitaux
51
(1975) 741-744.
4. Gottscha B., Fabriciu E.M., Patzug U.,
Padiatrie und Padologie
9
(1974) 48.
5. Travert G., Mustin C., Fernandez Y.,
J Gen Humaine
28
(1980) 141-144.
6. Lenoir G., Michalewski A., Moyse D., Madras M.B., Richardot P.M., Sorin M.,
Hennequet A.,
Clin Invest Med
10
(1987) A49.
7. Livshits L.A., Gorovenko N.G., Ivashchenko T.E., Buzhiyevskaya T.I.,
Vracheb-
noe Delo
4
(1990) 101-103.
8. Pajon A., Aguilaniu B.,
Rev Maladies Resp
9
(1992) 564-566.
9. Bachmann K.D.,
Med Welt
25
(1974) 249-252.
10. Moser H., Liechtigallati S., Braga S.,
J Clin Chem Clin Biochem
26
(1988)
724-725.
11. Rasche K., Poller W., Fisselereckhoff A., Wiebe V.,
Deutsche Med Wochenschr
114
(1989) 1566-1570.
