Biology Reference
In-Depth Information
Chapter 3
Marıa Isabel Pividori and Salvador Alegret
Grup deSensors iBiosensors, Departamentde Qu´ımica,
UniversitatAutonomadeBarcelona, Barcelona, Spain
Isabel.Pividori@uab.cat
This chapter reports the main features of rigid carbon-polymer
composite materials for electrochemical DNA biosensing. Novel
approaches based on composites modified with biomolecules (bio-
composites) and nanostructured materials (nanocomposites) for
the improved biosensingofDNA are also discussed.
3.1 Introduction
The use of nucleic acids as biorecognition elements represents an
exciting interdisciplinary area of research in converging technolo-
gies. The oriented and improved immobilization of single-stranded
DNA to solid substrates, followed by hybridization and detection
of this event, has gained importance over the past decade, due
to the growing demand for genetic information in an increasingly
