Biology Reference
In-Depth Information
Chapter 15
Chan Yean Yean
a*
, Lee Su Yin
b
, and Manickam Ravichandran
b
a
Department of Medical Microbiology and Parasitology, School of Medical Sciences,
Universiti Sains Malaysia, Kota Bharu, Malaysia
b
Faculty of Applied Sciences, AIMST University, 08100 Semeling, Kedah, Malaysia
*yeancyn@yahoo.com
Electrochemical genosensors for the detection of bacteria were
introduced about a decade ago. Miniaturization and advanced
microfabrication technology have made it compatible with bacteria
DNA diagnostic. This technology is cost effective, fast, and accurate.
The bioa
nity and biocatalysis reactions generate amperometric,
voltametric, impedimetric, or conductimetric signals on screen-
printedtransducerchips(SPC),whichisproportionaltothenumber
of immobilized DNA copies on the SPC surface. Electrochemical
genosensor assays give quantitative rather than qualitative results.
Furthermore, the use of a hand-held portable reader makes this
assay suitable for use in the field, especially for point-of-care (POC)
tests at the patient bedside, during surveillance and environmental
studies of microorganisms.
