Biology Reference
In-Depth Information
Chapter 11
Electrochemical Transducer for
Oligonucleotide Biosensor Based
on the Elimination and Adsorptive
Transfer Techniques
Libuse Trnkova,
a
Frantisek Jelen,
b
and Mehmet Ozsoz
c
a
Department of Chemistry, Faculty of Science, Masaryk University,
Kotlarska 2, CZ-611 37 Brno, Czech Republic
b
Institute of Biophysics, v.v.i., Academy of Sciences of the Czech Republic,
Kralovopolska 135, CZ-612 65 Brno, Czech Republic
c
Analytical Chemistry Department, Faculty of Pharmacy,
Ege University, 35100 Bornova, Izmir, Turkey
libuse@chemi.muni.cz
11.1 Introduction
Electrochemical biosensors are usually based on redox reactions
that consume or produce electrons. Such a device can be re-
presented by an indication electrode, which integrates receptor-
transducerelementprovidingselectivequantitativeanalyticalinfor-
mation;recordedsignalsareproportionaltoanalyteconcentrations.
There are several types of electrochemical transducers, from which
