Handling Copper: A Paradigm for the Mechanisms of Metal Ion Homeostasis - Environmental Contamination: Health Risks and Ecological Restoration - page 274

TABLE 13.1 (continued)
List.of.Copper.Traficking.Proteins.in.Bacterial.Models

CopperTransport-RelatedProteins
andRegulatoryElements CellularLocation Function Homologs References

Four-Component.Copper.Pump
CusCFBA

Inner.membrane,.
periplasm,.outer.
membrane

Cu(I).eflux Munson.et.al..(2000),.

Franke.et.al..(2003)

Multi-Copper.Oxidase
CueO

Periplasm Protection.of.the.periplasm.from.

copper-induced.damage

Grass.and.Rensing.(2001)

Targets.for.Cu(I)
Cu,Zn.SOD

Periplasm Enzyme.that.reduces.reactive.

oxidative.stress

Cytochrome.bo3 Periplasm Laccase.activity,.detoxiication? Osborne.et.al..(1999)

Transcriptional.Regulation
CueR Cytoplasm DNA-binding.regulator;.member.

of.the.MerR.family.of.metal-
responsive.regulators

Stoyanov.et.al..(2001),.
Outten.et.al..(2000)

cusRS Cytoplasm Chromosomal.two-component.

regulator

Munson.et.al..(2000)