Handling Copper: A Paradigm for the Mechanisms of Metal Ion Homeostasis - Environmental Contamination: Health Risks and Ecological Restoration - page 273

TABLE 13.1
List.of.Copper.Traficking.Proteins.in.Bacterial.Models

CopperTransport-RelatedProteins
andRegulatoryElements CellularLocation Function Homologs References

Bacteria
Enterococcus hirae
Reductase

Extracellular Reduces.Cu(II).to.Cu(I).for.uptake Ndh-2.( E. coli )

P-type.ATPase.Transporters
CopA

Plasma.membrane Cu(I).inlux.transporter Odermatt.et.al..(1993,.1994)

CopB Plasma.membrane Cu(I).eflux.transporter CopA.( E. coli ) Odermatt.et.al..(1993,.1994)

Cu.Metallochaperone
CopZ Cytoplasm Delivers.Cu(I).to.CopY Odermatt.and.Solioz.(1995),.

Cobine.et.al..(1999)

Transcriptional.Regulation
CopY

Cytoplasm Copper-responsive.repressor Odermatt.et.al..(1994).

Odermatt.and.Solioz.(1995)

E. coli
Reductase
NDH-2 Inner.membrane Reduces.Cu(II).to.Cu(I).for.uptake Rapisarda.et.al..(1999,.2002)

P-type.ATPase.Transporters
CopA

Inner.membrane Cu(I).eflux.transporter CopB.( Enterococcus

hirae )

Rensing.et.al..(2000)

(continued)