Biomedical Engineering Reference
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3. Gross, G.W. and Gopal, K.V. (2006) Emerging histiotypic properties of cultured neuronal net-
works. In: Advances in Network Electrophysiology using Microelectrode Arrays (M. Taketani
and M. Baudry, eds), Springer, pp. 193-214.
4. Xia, Y., Gopal, K.V., and Gross, G.W. (2003) Differential acute effects of fluoxetine on frontal
and auditory cortex networks in vitro. Brain Res. 973: 151-160.
5. Pancrazio, J.J., Keefer, E.W., Wu Ma, Stenger, D.A., and Gross, G.W. (2001) Neurophysiologic
evaluation of chemical agent hydrolysis products on cortical neurons in vitro . NeuroToxicology
22: 393-400.
6. Stenger, D.A., Gross, G.W., Keefer, E.W., Shaffer, K.M., Andreadis, J.D., Ma, W., and Pancrazio,
J.J. (2001) Detection of physiologically active compounds using cell-based biosensors. Trends
Biotechnol. 19: 304-309.
7. O'Shaughnessy, T.J., Gray, S.A., and Pancrazio, J.J. (2004) Cultured neuronal networks as envi-
ronmental biosensors. J. Appl. Toxicol. 24:379-385.
8. Pancrazio, J.J., Gray, S.A., Shubin, Y.S., Cuttino, D.S., Shaffer, K.M., Eisemann, K., Curran, A.,
Zim, B., Gross, G.W., and O'Shaughnessy, T.J. (2003) A portable microelectrode array record-
ing system incorporating cultured neuronal networks for neurotoxin detection. Biosens.
Bioelectron. 18: 1339-1347.
9. Kulagina, N.V., O'shaughnessy, T.J., Ma, W., Ramsdell, J.S., and Pancrazio, J.J. (2004)
Pharmacological effects of the marine toxins, brevetoxin and saxitoxin, on murine frontal cor-
tex neuronal networks. Toxicon 44:669-676.
10. Gopal, K.V. and Gross, G.W. (1996) Auditory cortical neurons in vitro: Initial pharmacological
studies. Acta Otolaryngologica 116: 697-704.
11. Keefer, E.W. and Gross, G.W. (2000) Spiking properties of respiratory-related pacemaker cells
in vitro. Society for Neuroscience Abstracts V26, Abst. # 347.7.
12. Ransom, B.R., Neale, E.A., Henkart, M., Bullock, P.N., and Nelson, P.G. (1977) Mouse spinal
cord in cell culture. J. Neurophysiol. 40: 1132-1150.
13. Gross, G.W., Wen, W., and Lin, J. (l985). Transparent ITO patterns for extracellular, multisite
recording in neuronal cultures. J. Neurosci. Meth. 15: 243-252.
14. Gross, G.W. and Kowalski, J.M. (1991) Experimental and theoretical analyses of random net-
work dynamics. In: Neural Networks, Concepts, Application and Implementations, Vol. 4
(P. Antognetti and V. Milutinovic, eds), Prentice Hall, N.J., pp. 47-110.
15. Gross, G.W. (1994) Internal dynamics of randomized mammalian neuronal networks in cul-
ture. In: Enabling Technologies for Cultured Neural Networks (D.A. Stenger and T.M.
McKenna, eds), Academic Press, N.Y., pp. 277-317.
16. Xia, Y. and Gross, G.W. (2003) Histiotypic electrophysiological responses of cultured neuronal
networks to ethanol. Alcohol 30: 167-174.
17. Morefield, S. I., Keefer, E.W., Chapman, K. D., and Gross, G.W. (2000) Drug evaluations using
neuronal networks cultured on microelectrode arrays. Biosens. Bioelectron. 15: 383-396.
18. Keefer, E.W., Norton, S.J., Boyle, N.A.J., Talesa, V., and Gross, G.W. (2001b) Acute toxicity
screening of novel AChE inhibitors using neuronal networks on microelectrode arrays.
NeuroToxicology 22 (1): 3-12.
19. Oli-Rijal, S. (2005) Determination of dissociation constants for GABAA receptor antagonists
using spontaneously active neuronal networks in vitro . MS Thesis, University of North Texas,
December 2005.
20. Johnston, G.A., Curtis, D.R., De Groat W.C., and Duggan, A.W. (1968) Central actions of
ibotenic acid and muscimol. Biochem. Pharmacol. 17: 2488-2489.
21. Chambon, J.P., Duggan, A.W., Heaulme, M., Restle, S., Schlichter, R., Biziere, K., Wermuth,
C.G. (1985) An arylaminopyridazine derivative of gamma-aminobutyric acid (GABA) is a
selective and competitive antagonist at the GABA A receptor site. Neurobiology 82: 1832-1836.
22. Heaulme, M., Chambon, J.P., Leyris, R., Wermuth, C.G., and Biziere, K. (1986) Biochemical
characterization of the interaction of three pyridazinyl GABA derivatives with the GABA A
receptors sites. Brain Res . 384: 224-231.
23.
Arunlakshana, O. and Schild, H.O. (1959) Some quantitative use of drug antagonists. Br. J.
Pharmacol . 14: 48-58.
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