Biomedical Engineering Reference
In-Depth Information
89. Vigna E, Cavalieri S, Ailles L et al (2002) Robust
and effi cient regulation of transgene expression
in vivo by improved tetracycline-dependent len-
tiviral vectors. Mol Ther 5:252-261
90. Galimi F, Saez E, Gall J et al (2005)
Development of ecdysone-regulated lentiviral
vectors. Mol Ther 11:142-148
91. Georgievska B, Jakobsson J, Persson E et al
(2004) Regulated delivery of glial cell line-
derived neurotrophic factor into rat striatum,
using a tetracycline-dependent lentiviral vec-
tor. Hum Gene Ther 15:934-944
92. Brown BD, Gentner B, Cantore A et al (2007)
Endogenous microRNA can be broadly
exploited to regulate transgene expression
according to tissue, lineage and differentiation
state. Nat Biotechnol 25:1457-1467
93. Brown BD, Venneri MA, Zingale A et al
(2006) Endogenous microRNA regulation
suppresses transgene expression in hemato-
poietic lineages and enables stable gene trans-
fer. Nat Med 12:585-591
94. Stegmeier F, Hu G, Rickles RJ et al (2005) A
lentiviral microRNA-based system for single-
copy polymerase II-regulated RNA interfer-
ence in mammalian cells. Proc Natl Acad Sci
U S A 102:13212-13217
95. Labrador M, Corces VG (2002) Setting the
boundaries of chromatin domains and nuclear
organization. Cell 111:151-154
96. Sarkis C, Philippe S, Mallet J et al (2008)
Non-integrating lentiviral vectors. Curr Gene
Ther 8:430-437
97. Apolonia L, Waddington SN, Fernandes C
et al (2007) Stable gene transfer to muscle
using non-integrating lentiviral vectors. Mol
Ther 15:1947-1954
98. Philippe S, Sarkis C, Barkats M et al (2006)
Lentiviral vectors with a defective integrase
allow effi cient and sustained transgene expres-
sion in vitro and in vivo. Proc Natl Acad Sci U
S A 103:17684-17689
99. Rahim AA, Wong AM, Howe SJ et al (2009)
Effi cient gene delivery to the adult and fetal
CNS using pseudotyped non-integrating len-
tiviral vectors. Gene Ther 16:509-520
100. Lombardo A, Genovese P, Beausejour CM
et al (2007) Gene editing in human stem cells
using zinc fi nger nucleases and integrase-
defective lentiviral vector delivery. Nat
Biotechnol 25:1298-1306
101. Baum C (2007) Insertional mutagenesis in
gene therapy and stem cell biology. Curr
Opin Hematol 14:337-342
102. Blomer U, Kafri T, Randolph-Moore L et al
(1998) Bcl-xL protects adult septal choliner-
gic neurons from axotomized cell death. Proc
Natl Acad Sci U S A 95:2603-2608
103. de Almeida LP, Ross CA, Zala D et al (2002)
Lentiviral-mediated delivery of mutant hun-
tingtin in the striatum of rats induces a
selective neuropathology modulated by poly-
glutamine repeat size, huntingtin expression
levels, and protein length. J Neurosci 22:
3473-3483
104. Deglon N, Hantraye P (2005) Viral vectors as
tools to model and treat neurodegenerative
disorders. J Gene Med 7:530-539
105. Regulier E, Trottier Y, Perrin V et al (2003)
Early and reversible neuropathology induced
by tetracycline-regulated lentiviral overex-
pression of mutant huntingtin in rat striatum.
Hum Mol Genet 12:2827-2836
106. Kirik D, Annett LE, Burger C et al (2003)
Nigrostriatal alpha-synucleinopathy induced
by viral vector-mediated overexpression of
human alpha-synuclein: a new primate model
of Parkinson's disease. Proc Natl Acad Sci U S
A 100:2884-2889
107. Kirik D, Rosenblad C, Burger C et al (2002)
Parkinson-like neurodegeneration induced by
targeted overexpression of alpha-synuclein in the
nigrostriatal system. J Neurosci 22:2780-2791
108. Lo Bianco C, Ridet JL, Schneider BL et al
(2002) alpha-Synucleinopathy and selective
dopaminergic neuron loss in a rat lentiviral-
based model of Parkinson's disease. Proc Natl
Acad Sci U S A 99:10813-10818
109. Lo Bianco C, Schneider BL, Bauer M et al
(2004) Lentiviral vector delivery of parkin
prevents dopaminergic degeneration in an
alpha-synuclein rat model of Parkinson's
disease. Proc Natl Acad Sci U S A 101:
17510-17515
110. Tiscornia G, Tergaonkar V, Galimi F et al
(2004) CRE recombinase-inducible RNA
interference mediated by lentiviral vectors.
Proc Natl Acad Sci U S A 101:7347-7351
111. Ventura A, Meissner A, Dillon CP et al (2004)
Cre-lox-regulated conditional RNA interfer-
ence from transgenes. Proc Natl Acad Sci U S
A 101:10380-10385
112. Akkina RK, Walton RM, Chen ML et al
(1996) High-effi ciency gene transfer into
CD34+ cells with a human immunodefi ciency
virus type 1-based retroviral vector pseudo-
typed with vesicular stomatitis virus envelope
glycoprotein G. J Virol 70:2581-2585
113. Reiser J, Harmison G, Kluepfel-Stahl S et al
(1996) Transduction of nondividing cells
using pseudotyped defective high-titer HIV
type 1 particles. Proc Natl Acad Sci U S A
93:15266-15271
114. Reiser J, Lai Z, Zhang XY et al (2000)
Development of multigene and regulated len-
tivirus vectors. J Virol 74:10589-10599
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