Unattached Fraction of Radon Progeny as an Experimental Tool in the Assessment of the Risk of Nanoparticles* - Aerosols: Measurement, Dosimetry, and Health Effects - page 415

16 Unattached Fraction of Radon

Progeny as an Experimental
Tool in the Assessment of
the Risk of Nanoparticles*

Lev S. Ruzer

CONTENTS
16.1 Nanoaerosols: Dosimetric Road Map ................................................................................... 417
16.1.1 Introduction .............................................................................................................. 417
16.1.2 Nanoparticle.............................................................................................................. 417
16.1.3 Nanorisk.................................................................................................................... 418
16.1.4 Airborne Nanoparticle Concentration Measurement ............................................... 420
16.1.5 Nanoparticle Respirators True Eficiency Measurements ........................................ 421
16.1.5.1 Conclusions ................................................................................................ 421
16.1.6 Nanoparticle Deposition in the Lung (Right Branch of the Dosimetric
Road Map) ................................................................................................................ 422
16.1.7 Cellular Entering Mechanisms ................................................................................. 423
16.1.7.1 Conclusions ................................................................................................ 423
16.2 Radon Progeny as an Experimental Tool for Dosimetry of Nanoaerosols........................... 424
16.2.1 Approach: Safety of Radioactive Markers in Aerosol Exposure Study ................... 425
16.2.2 Characteristics of Radon Progeny ............................................................................ 426
16.2.3 Assessment of Particle Deposition in Lungs ............................................................ 426
16.2.4 Radon Progeny as a Tool in the Assessment of Particle Surface Area..................... 428
16.2.5 Method and Calibration Procedure .......................................................................... 429
16.2.6 Discussion and Conclusions...................................................................................... 432
References...................................................................................................................................... 435

I think it makes sense to analyze the relationship between nanoaerosol measurements and the
health effect by comparing the studies on health effect associated with radon and its decay products
and nanoaerosols especially because we are now at the beginning of a new global problem—the
assessment of the dose and health effect of nanoparticles.
The similarity in both cases is that we have to study two groups of separate problems—dosimetry
and health effect.
The difference is that in the case of radiation in general and the problem of radon and its prog-
eny in particular, there were many studies on the correlations between radon and its progeny both

* I dedicate this chapter to my best friend, Professor Tatjana Tolstikova.

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