Medical and Pharmaceutical Aerosols - Aerosols: Measurement, Dosimetry, and Health Effects - page 19

TABLE 1.5
Drugs Delivered by the Inhalation Route

Product Active Dose/Inhalation Dose/Day

MDI a
Atrovent HFA

Ipratropium bromide HFA 2 inhalations 4 times, max

12 times (136-204 μg)

17 μg

Azmacort Triamcinolone acetonide 2 inhalations 3-4 times or

4 inhalations bid, max
16 times (0.45-1.2 mg)

75 μg

Combivent
inhalation aerosol

Ipratropium bromide and
albuterol sulfate

2 inhalations 4-6 times
(0.14/0.82-0.216/1.24 mg)

18/103 μg

Dulera Mometasone furoate and

formoterol fumarate dihydrate

2 inhalations bid
(400/20-800/40 μg) 197

100/5 μg
200/10 μg

Flovent HFA Fluticasone propionate 44 μg

110 μg
220 μg

2 inhalations bid
(0.176-0.880 mg)

Maxair autohaler Pirbuterol acetate 2 inhalations 4-6 times

(1.6-2.4 mg)

200 μg

Proventil HFA Albuterol sulfate 1-2 inhalations 4-6 times

(0.432-1.296 mg)

108 μg

Qvar Beclomethasone dipropionate 40 μg

80 μg

2 inhalations bid
(0.16-0.320 mg)

Symbicort Budesonide and formoterol

fumarate dihydrate

2 inhalations bid
(320/18-640/18 μg)

80/4.5 μg
160/4.5 μg

Xopenex HFA Levalbuterol tartrate 45 μg 1-2 inhalations 4-6 times

(0.18-0.540 mg)

DPI a
Advair Diskus

Fluticasone propionate and
salmeterol xinafoate

1 inhalation bid
(0.186/0.090-0.330/
0.090 mg)

93/45 μg
165/45 μg
233/45 μg

Asmanex
Twisthaler

Mometasone furoate 100 μg

200 μg

1-2 inhalations 1-2 times
(0.1-0.4 mg)

Foradil Aerolizer Formoterol fumarate 1 inhalation bid (0.02 mg)

10 μg

Pulmicort lexhaler Budesonide 90 μg

180 μg

1-4 inhalations bid
(0.18-1.44 mg)

Relenza Zanamivir 4 mg 2 inhalations bid (16 mg)

Serevent diskus Salmeterol xinofoate 50 μg 1 inhalation bid (0.1 mg)

Spiriva Handihaler Tiotropium bromide

18 μg 1 inhalation bid (36 μg)

Nebulizer b
Accuneb

Albuterol sulfate 1.25 mg/3 mL

0.63 mg/3 mL

1 nebulization 3-4 times as
needed (5 mg)

Atrovent solution Ipratropium bromide 0.02%

500 μg/2.5 mL

1 nebulization 3-4 times
(2 mg)

Duoneb solution Ipratropium bromide/Albuterol

sulfate

0.5/3.0 mg/3 mL
42%/46%/3 mL

1 nebulization 3 times
(1.5/9.0 mg)

Perforomist Fomoterol fumarate 1 nebulization bid for a

maximum of 40 μg
( continued )

20 μg/2 mL