Modeling Deposition of Inhaled Particles - Aerosols: Measurement, Dosimetry, and Health Effects - page 113

1.0
0.9
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0. 0.01

1.0
0.9
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0. 0.01

Model 7,29
Experiment 236

Model 7,29
Experiment 236

0. 1 1 10 100 1 10 100

0. 1

(A) Particle size (µm) (B) Particle size (µm)

1.0
0.9
0.8
0.7
0.6
0.5
0.4
0.3
0.2
0.1
0. 0.01

Model 7,29
Experiment 236

1 10 100

0. 1

(C) Particle size (µm)

FIGURE 5.16 Model predictions of pulmonary deposition determined using the deterministic model of
Martonen, 7,31 plotted against experimental data. 281 (A) Breathing frequency = 30 breaths/min, tidal volume =
500 mL, (B) breathing frequency = 15 breaths/min, tidal volume = 1000 mL, and (C) breathing frequency = 30
breaths/min, tidal volume = 1500 mL.

Particle size (µm) Particle size (µm)

0.14
0.12
0.10

0.14
0.12
0.10

0.05 0.05

0.1
1.0
5.0
10.0

0.1
1.0
5.0
10.0

0.08
0.06
0.04
0.02
0.0

0.08
0.06
0.04
0.02
0.0

0 2 4 6 8 10 12 14 16 18 20 22 0 2 4 6 8 10 12 14 16 18 20 22

(A) Generation (B) Generation

Particle size (µm)

0.14
0.12
0.10

0.05

0.1
1.0
5.0
10.0

0.08
0.06
0.04
0.02
0.0

0 2 4 6 8 10 12 14 16 18 20 22

(C) Generation

FIGURE 5.17 Model predictions of particle deposition generation-by-generation determined using the
deterministic model of Martonen, 7,31 for a range of particle sizes. (A) Breathing frequency = 30 breaths/min,
tidal volume = 500 mL, (B) breathing frequency = 15 breaths/min, tidal volume = 1000 mL, and (C) breathing
frequency = 30 breaths/min, tidal volume = 1500 mL.