Modeling Deposition of Inhaled Particles - Aerosols: Measurement, Dosimetry, and Health Effects - page 99

TABLE 5.1
Temperatures and RH in the Human Respiratory Tract, for Both Inspiration and Expiration

Nasal Oral

Anatomical
Location

References

T insp (°C) T exp (°C) RH insp RH exp T insp (°C) T exp (°C) RH insp RH e xp

Nasal Passages
Distance from nostril
1.5 cm 28.9 ± 2.3 — 69 ± 6.5 — — — — — Keck et al. 134

2.5 cm 30.3 ± 1.6 — 78.7 ± 7.2 — — — — — Keck et al. 134

6.0 cm 32.6 ± 1.5 — 90.3 ± 5.3 — — — — — Keck et al. 134

Laryngeal cavity 32.3 ± 0.8 36.4 ± 0.2 98-99 98-99 30.6 ± 0.8 36.2 ± 0.3 90 99 Ingelstedt 135

Airway generation, i
i = 0 (trachea)

34-35 36-37 — — 33-34 36-37 — — Cole 136

i = 0 (trachea) 35.3 35.7 98 99.9 — — — — Perwitzschky 137

i = 0 (trachea) 35.4 36.2 — — 34.5 35.8 — — Verzar et al. 138

i = 0 (trachea) 32.6 35.3 — — 32.9 34.4 — — Herlitzka 139

i = 0 (trachea) — — — — 26.7 — 82.7 — Dery et al. 140

i = 0 (trachea) — — — — 31.4-31.9 33.2-33.4 73.6-80.4 — Dery 141

i = 0 (trachea) — — — — 31.2 32.6 — — McFadden et al. 142

i = 0 (trachea) — — — — 32 33 — — McFadden et al. 142

i = 0 (trachea) — — — — 32.2 33.4 — — Dery et al. 140

i = 0 (trachea) 36 36.2 98.3 99.2 — — — — McRae et al. 143

i = 1 (main) — — — — 30.6 — 85.8 — Dery 141

i = 1 (main) — — — — 32.2 33.7 87 — McFadden et al. 142

i = 2 (lobar) — — — — 33 34 — — McFadden et al. 142

i = 3 (segmental) — — — — 33.1 — 91.3 — Dery et al. 140

i = 4 (subsegmental) — — — — 33.9 — 94.6 — McFadden et al. 142

i = 4 - 5 — — — — 33.9 35 — — Dery 141

i = 10 - 11 — — — — 34.6 36 — — McFadden et al. 142

Source: Adapted from Extrapolation of Dosimetric Relationships for Inhaled Particles and Gases , Martonen, T.B., Hoffman, W., Eisner, A.D., and
Ménache, M.G., The role of particle hygroscopicity in aerosol therapy and inhalation toxicology, pp. 303-316, Copyright 1989, with permis-
sion from Elsevier.