Biology Reference
In-Depth Information
Microporous-
chitosan tube
Filaments
Polyglycolic acid
(PGA) oriented
filaments
37-
years-old
male
human
patient
Median
nerve
Nerve
discontinuity
35
JAMAR Hand
evaluation Kit
(5030KIT), touch test
sensory evaluators,
disk-criminator,
electrophysiological
evaluation, blood and
urinary test, and
serum biochemical
examination
-
3 years
Motor and
sensory function
recovery
Fan et al.
(2008)
Laser-
activated
chitosan
adhesive
-
-
Rats
Tibial and
sciatic nerve
Sutureless
anastomosis
-
Histological
evaluation
-
3 days
Successful nerve
anastomosis;
myelinated
axons display
normal number
and morphology
Lauto et al.
(2008)
Bilayered
chitosan film
tube
Nano-/
microfibers
Nano-/
microfibers mesh
tube with a DAc
of 78% or 93%
and film tube
with a DAc of
93%
Male
Sprague-
Dawley
rats
Sciatic nerve Nerve
transection
15
Von Frey hair test,
Static toe spread
factor (STSF),
electrophysiological
and histological
evaluation
15-mm
autograft
10 weeks
Functional
recovery of
motor activity
delays in each
group compared
to autograft
group; good
sensory and
functional
recovery in
autograft group
followed by
nano-/
microfibers
mesh tubes with
a DAc of 93%
group
Wang et al.
(2008) and
Wang, Itoh,
Matsuda,
Ichinose,
et al. (2008)
Continued
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