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Pheromone
Osmotic Stress
Hypotonic Shock
MAPKKK
MAPKKK
MAPKKK
MAPKK
MAPKK
MAPKK
MAPK
MAPK
MAPK
Mating
Osmoadaptation
Cell Wall Growth
Figure 2.2 Parallel MAP kinase cascades in yeast.
information ranges from the quantum-mechanical to the social or ecological,
and we have illustrated our view of proteins as smart computational agents with
a discussion of cascades in intracellular signaling pathways. Further aspects of
the mathematical and computational modeling of these processes are described
by Fisher et al. [6].
References
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Theor. Biol. , 184:331-338, 1997.
[2] M. Conrad. The price of programmability. In H. Herken, editor, The Universal
Turing Machine: A Fifty Year Survey , pages 285-307. Oxford University Press,
Oxford, 1988.
[3] M. Conrad. Quantum mechanics and cellular information processing: the self-
assembly paradigm. Biomed. Biochim. Acta , 49(8-9):743-755, 1990.
[4] M. Conrad. The seed germination model of enzyme catalysis. BioSystems , 27:223-
233, 1992.
[5] P. Devine and R. C. Paton. Biologically-inspired computational ecologies: a case
study. In David Corne and Jonathan L. Shapiro, editors, Evolutionary Computing,
AISB Workshop , vol. 1305, Lecture Notes in Computer Science , pages 11-30.
Springer, Berlin, 1997.
[6] M. Fisher, G. Malcolm, and R. C. Paton. Spatio-logical processes in intracellular
signalling. BioSystems , 55:83-92, 2000.
[7] M. Fisher, R. C. Paton, and K. Matsuno. Intracellular signalling proteins as 'smart'
agents in parallel distributed processes. BioSystems , 50:159-171, 1999.
 
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