Chemistry Reference
In-Depth Information
Hydroxypropyl Cellulose
Structure
RO
O
OH
RO
OR
, R is H or [CH
2
CH(CH
3
)O]
m
H
O
O
OR
OR
O
H
OR
n/
2
Synonyms
HPC, Hyprolose, oxypropylated cellulose,
Klucel
Molecular weight range
(g/mol)
50,000
-
1,250,000
Solubility parameter,
δ
(MPa
0.5
)
31.5
T
g
range (
°
C)
100-150
Water uptake (% water at
75% RH)
4% (@50% RH)
12% (@84% RH)
Solvent solubility
Soluble 1 in 10 parts dichloromethane; 1 in
2.5 parts ethanol (95%); 1 in 2 parts
methanol; 1 in 5 parts propan-2-ol; 1 in 5
parts propylene glycol
pH range where soluble
1-10
Amenable methods of
dispersion manufacture
Melt extrusion, spray drying
Use in marketed dispersion
products
None
Grade
MW
Moisture
content (%)
EF
80,000
0.59
LF
95,000
2.21
JF
140,000
1.44
GF
370,000
1.67
MF
850,000
1.52
HF
1,150,000
4.27
