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88. De Buck, S., Singa, V., Fenu, L., Nijsen, M., Mackie, C., and Gilissen, R. (2007) Prediction
of human pharmacokinetics using physiologically based modeling: a retrospective analysis
of 26 clinically tested compounds. Drug Metab. Dispos. , 35:1766-1780.
89. Shono, Y., Jantratid, E., and Dressman, J. (2011) Precipitation in the small intestine may play
a more important role in the in vivo performance of poorly soluble weak bases in the fasted
state: case example nelfinavir. Eur. J. Pharm. Biopharm. , 79:349-356.
90. Sugano, K. (2009) A simulation tool of oral absorption using classical nucleation theory. Int.
J. Pharm. , 378:142
145.
91. Sugano, K. (2009) Introduction to computational oral drug simulation. Expert Opin. Drug
Metab. Toxicol. , 5:259-293.
92. Ozaki, S., Kushida, I., Yamashita, T., Hasebe, T., Shirai, O., and Kano, K. (2012) Evaluation
of drug supersaturation by thermodynamic and kinetic approaches for the prediction of oral
absorbability in amorphous pharmaceuticals. J. Pharm. Sci. , 101:4220-4230.
93. Greco, K. and Bogner, R. (2012) Solution-mediated phase transformations: significance
during dissolution and implications for bioavailability. J. Pharm. Sci. , 101:2996-3018.
94. Verreck, G., Vandecruys, R., De Conde, V., Baert, L., Peeters, J., and Brewster, M. (2004)
The use of three different solid dispersion formulations - melt extrusion, film-coated beads,
and a glass thermoplastic system - to improve the bioavailability of a novel microsomal
triglyceride transfer protein inhibitor. J. Pharm. Sci. , 93:1217-1228.
95. Brewster, M., Vandecruys, R., Verreck, G., Noppe, M., and Peeters, J. (2003) A novel
cyclodextrin-containingglass thermoplastic systems (GTS) for formulatingpoorlywater soluble
drug candidates: preclinical and clinical results. J. Incl. Phenom. Macrocycl. Chem. , 44:38-39.
96. Vandecruys, R., Verreck, G., Peeters, J., and Brewster, M. (2007) A surfactant-based glass
thermoplastic system (GTS) for formulating poorly water-soluble weak base drug candidates.
Abstracts, 34th Annual Meeting and Exposition of the Controlled Release Society, Long
Beach, CA, July 7-11, 2007 .
97. Peeters, J., Neeskens, P., Tollenaere, J. P., Van Remoortere, P., and Brewster, M. (2002)
Characterization of the interaction of 2-hydroxypropyl- β -cyclodextrin with itraconazole at
pH 2, 4 and 7. J. Pharm. Sci. , 91:1414-1422.
98. Six, K., Verreck, G., Peeters, J., Binnemans, K., Berghmans, H., Augustijns, P., Kinget, R.,
and Van den Mooter, G. (2001) Investigation of thermal properties of glassy itraconazole:
identification of a monotropic mesophase. Thermochim. Acta , 376:175-181.
99. Gilis, P., De Conde, V., and Vandecruys, R. (1997) Beads having a core coated with an
antifungal and a polymer. U.S. Patent 5,633,015.
100. Verreck, G., Six, K., Van den Mooter, G., Baert, L., Peeters, J., and Brewster, M. (2003)
Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose
prepared by melt extrusion: Part 1. Int. J. Pharm. , 251:165-174.
101. Engers, D., Teng, J., Jimenez-Novoa, J., Gent, P., Hossack, S., Cambell, C., Thomson, J.,
Ivanisevic, I., Templeton, A., Byrn, S., and Newman, A. (2010) A solid-state approach to
enable early development compounds: selection and animal bioavailability studies of an
itraconazole amorphous solid dispersion. J. Pharm. Sci. , 99:3901-3922.
102. Six, K., Daems, T., de Hoon, J., Van Hecken, A., Depre, M., Bouche, M., Verreck, G.,
Peeters, J., Brewster, M., and Van den Mooter, G. (2005) Clinical studies of solid dispersions
of itraconazole prepared by hot-stage extrusion. Eur. J. Pharm. Sci. , 24:179-186.
103. Kakuda, T., Schöller-Gyüre, M., Workman, C., Arasteh, K., Pozniak, A., De Smedt, G.,
Beets, G., Peeters, M., Vandermeulen, K., Woodfall, B., and Hoetelmans, R. (2008) Single
-
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