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Figure 4.17. SEM-EDS mapping of a particle of an amorphous solid dispersion containing 20%
(w/w) of 6-(2-(5-chloro-2-(2,4-di uorobenyzloxy)phenyl)cyclopent-1-enyl)picolinic acid in HPC
[86,109]. Images were obtained using a Hitachi 3500 SEM equipped with a Bruker AXS Quantax
X ash AXS SDD energy-dispersive X-ray detector. In (a), a BSE topological image is shown. EDS
maps of X-ray emission for (b) chlorine, (c) oxygen, and (d) fluorine are shown. More intense
false-color map points in (b), (c), and (d) indicate a higher concentration of each element.
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