Chemistry Reference
In-Depth Information
Aryl fluorines
(a)
Contact time = 100
ยต
s
0.5
1.0
1.5
2.0
2.5
Aliphatic
protons
3.0
3.5
4.0
4.5
5.0
5.5
Drug-polymer
interaction
6.0
6.5
7.0
Aromatic
protons
7.5
8.0
-100
-105
-110
-115
-120
-125
19
F chemical shift (ppm from CFCl
3
)
Aryl fluorines
(b)
Contact time = 2 ms
0.5
1.0
1.5
2.0
2.5
3.0
Aliphatic
protons
3.5
4.0
4.5
5.0
5.5
6.0
Drug-polymer
interaction
6.5
7.0
Aromatic
protons
7.5
8.0
-100
-105
-110
-115
-120
-125
19
F chemical shift (ppm from CFCl
3
)
