Biomedical Engineering Reference
In-Depth Information
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Figure 3.14
(A) Schematic representation of co-culturing of neurons and glial cells on
a microfluidic platform with flow of from the glial side to the neuronal
chamber established through higher culture media level on the glia side.
(B) Image of co-culture platform with (C) showing a zoom image of the
glia compartment on the left and neurons compartment on the right
separated by the barrier valves.
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(Reprinted by kind permission of Elsevier BV.)
Figure 3.15, migrate on a low anity substrate toward a high anity substrate
on adhesive templates, which they adhere to and assemble on.
3.8 In Vitro Microelectrodes Arrays
Specific measures are followed in order to study the activity and development
of neuronal cell networks in culture or in brain slices. To begin with, planar
biosensor arrays are built over embedded electrodes to overcome the challenges
of probing a large number of neurons simultaneously using classic glass
