Biomedical Engineering Reference
In-Depth Information
3.7.1 Regeneration Sieves and Cone-ingrowth Electrodes
When nerve regeneration is envisaged with the intention to regain lost function,
two-way interfaces are inserted transversally into the severed nerve. The nerve
fascicules slowly grow through the orifices provided. At the same time, the
fascicules remain in contact with the electrodes constructed around the
respective metalized holes and are strongly fixed to the device in place, which
cannot move. This subsequently causes the development of scar tissue because
of mechanical micro displacements. Figure 3.11 shows how a planar
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Figure 3.11
(a) Schematic of a designed silver array neural interface implanted to an
intersected nerve. (b) Schematic of silicon chamber with a chip bridging
the 4mm gap between the proximal and distal stumps of rat sciatic
nerve.
45,46
(Reprinted by kind permission of Elsevier BV.)
