Release, Transport and Toxicity of Engineered Nanoparticles - Reviews of Environmental Contamination and Toxicology - page 20

Table 5 (continued)

Nanoparticle studied Concentration used Organism studied Observed effects References

Ag 1.03mg/L Japanesemedaka Acute toxicity, Oedema and abnormalitites in

heart, ins, brain, spine and eyes,
developmental, histopathological abnormalities

Wuetal.( 2010 )

Ag - Zebraish embryo Abnormal phenotypic appearance, distribution

inheart,brain,yolkandblood

Asharanietal.( 2008 )

Ag Japanesemedaka Cellular and DNA damage, oxidative stress

and carcinogenecity

Chaeetal.( 2009 )

Ag 1 ʼg/L Japanesemedaka(Male) Oxidative and inlammatory stress Phametal.( 2012 )

Fluorescent Latex NP 10mg/L Seethroughmedaka Accumulation in gills and intestine and other

organs

Kashiwada( 2006 )

Mammals
Fullerenolandquartz

0.02, 0.2, 20 and 200 ʼg/
mouse

Mice Lung inlammation caused by neutrophils Roursguardetal.( 2008 )

Carbon nanotubes
(SWNTsandMWNTs),
TiO 2 , Cadmium particle
andmetaloxide(TiO 2 )

0.1-12.5mg/kg
(nanotubes),0.5-10mg/L
(TiO 2 ), 70 ʼg/L(cadmium),
1-5mg(Metaloxide)

Rats Lung damage, pulmonary inlammation,

activation of histocompatibility complex,
alveolar inlammation

HandyandShaw( 2007 )

Mice
Guineapig
hamsters

Carbon nanotubes 0.1 or 0.5 mg mice Lung inlammation, necrosis Lametal.( 2004 )

PolyalkylsulphonatedC 60 - Rats Accumulationinliver,kidneyandspleen Chenetal.( 1998 )

14-C labeled C 60 - Sprague-DawleyRats(Female) Long term accumulation in liver Bullard-Dillard et al.

( 1996 )

MWNTs 0.5, 2 or 5 mg Sprague-Dawley rats Pulmonary lesions and TNF-ʱ production Mulleretal.( 2005 )

SWNTs 1-5mg/kg Rats Transientinlammationandcellularinjury Warheitetal.( 2004 )

ZnO 5g/kg Adult mice Obstruction in intestine, severe symptoms Wangetal.( 2006 )

ZnO 6mg/m 3 Guineapig Decreased lung function Conneretal.( 1985 )