New Insights into the Role of BubR1 in Mitosis and Beyond - International Review of Cell and Molecular Biology - page 230

Table 6.2 Proteins interacting with BubR1
Protein Presumed role References

Cdc20 MCC assembly (anaphase
inhibition)

Hardwick et al. (2000) , Sudakin et al.
(2001) , and Tang et al. (2001)

Mad2 MCC assembly (anaphase

inhibition)

Chao et al. (2012) and Tian et al. (2012)

Bub3 MCC assembly (anaphase

inhibition)
Kinetochore binding

Hardwick et al. (2000) , Jablonski et al.
(1998) , Taylor et al. (1998) ,
and Fraschini et al. (2001)

Bub1 Kinetochore binding

KNL1 Kinetochore binding Krenn et al. (2012) , Kiyomitsu et al.

(2007, 2011) , and Bolanos-Garcia et al.
(2011)

CenpE Regulation of kinase activity?
Regulation of K-MT
attachment

Chan et al. (1998) , Abrieu et al. (2000) ,
and Mao et al. (2003, 2005)

Ajuba Microtubule regulation Ferrand et al. (2009)

BRCA2 Acetylation and stabilization
of BubR1 during
prometaphase

Choi et al. (2012)

PCAF Acetylation and stabilization of

BubR1 during prometaphase

Choi et al. (2009)

BCSG1 Destabilizes BubR1 Gupta et al. (2003)

B56/
PP2a

Phosphatase opposing
AurB on unattached
kinetochores

Suijkerbuijk et al. (2012b)
and Kruse et al. (2013)

PARP-1 DNA damage response Fang et al. (2006)

P53 P53 activation in response

to spindle damage

Ha et al. (2007)

HBx Attenuates BubR1 binding

to Cdc20

Kim et al. (2008)

Tap73 P53 family protein activation Tomasini et al. (2009)