Biology Reference
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A
Closed mitosis
B
Semi open mitosis
C
Matrix confined
D
Non protein structural elements
Figure 3.8 Components of the nucleus or nonprotein macromolecules may provide
structural support or sequestration of spindle components from the surrounding cyto-
plasm. (A) Closed mitosis occurs completely within the nuclear envelope. (B) In semi-
open mitosis, the nuclear envelope has openings sufficient to allow large structures
like MTs to pass through, or has broken down into fragments but is not completely dis-
assembled. (C) A proteinaceous matrix or meshwork interacts with and surrounds the
spindle, providing a means for sequestering some large protein complexes or resisting
forces. (D) Nonprotein macromolecules contribute to spindle assembly by interacting
with spindle components either internally or externally like the proteinaceous matrix.
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