Biomedical Engineering Reference
In-Depth Information
Cyclopamine analog
Hedgehog pathway
signaling inhibitor; IC
50
=
33
M
MTS proliferation assay
of A549 cells
101
Three-ring 2-naphthol
analog
5-Lipoxygenase
inhibitor; IC
50
=
3
M
Human blood cell assay
102
Tetrahydroisoquinoline
analog
Estrogen receptor
agonist; EC
50
=
Recruitment of a
fluorescent binder of the
agonist-bound receptor
102
20
M
for ER
,EC
50
=
4.6
M for ER
Fingolimod and
myriocin analog
Sphingosine kinase 2
inhibitor; 2.1% SphK2
activity at 100
M
Scintillation
spectrometry of
32
P
103
