Biomedical Engineering Reference
In-Depth Information
1,3-Dioxane uretupamine
B
Transcription factor
repressor Ure2p binder;
K
d
=
7.5
M
Small-molecule
microarray binding
screen
32
Tertiary amide fexaramine
Farnesoid X receptor
(FXR) agonist; EC
50
=
25 nM
Cell-based transcription
assay with an
FXR-responsive
luciferase reporter
33
Dihydropyrancarboxamide
haptamide B
Yeast transcription
factor Hap3p inhibitor;
K
d
=
0.33
M
Small-molecule
microarray binding
screen
34
(
continued
)
