Biomedical Engineering Reference
In-Depth Information
(a)
(b)
(c)
FIGURE 2.1
(a) Mitotic spindle kinesin (Eg5) inhibitor monastrol, made by the Biginelli
3CR. (b) Priaxon's MDM2-p53 inhibitor, made by the Shaw 4CR and amide coupling. (c)
Praziquantel (
11
, Ugi 4CR), GSK's oxytocin antagonist (
12
, Ugi 4CR), clopidogrel (
13
, Ugi
3CR and Petasis 3CR), and bicalutamide (
14
, Passerini 3CR).