DIVERSITY-ORIENTED SYNTHESIS AND DRUG DEVELOPMENT: FACILITATING THE DISCOVERY OF NOVEL PROBES AND THERAPEUTICS - Diversity-Oriented Synthesis - page 556

TABLE 17.3 ( Continued )

Growth
Inhibition
(Dd2, EC 50 , nM)

Growth
Inhibition
(Dd2, EC 50 , nM)

Solubility
(Water, M)

Solubility
(Water, M)

R R

400 2.2 4300 < 0.5

240 45 > 5000 1.2

2400 — > 5000 280