Biomedical Engineering Reference
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SCHEME 7.26 Transformation of furan precursors into three diverse scaffolds. Reagents and
conditions: (i) NBS, NaHCO 3 , NaOAc, THF/H 2 O (4 : 1), rt, 1 h; (ii) PPTS, DCM, 40 C, 20 h.
SCHEME 7.27 Conversion of 2-vinylbenzamides to fused isoindolinones. Reagents and
conditions: (i) OsO 4 /NaIO 4 /DABCO, THF/H 2 O (1 : 1); (ii) 50% TFA/DCM; (iii) 0.1 M
NaOH (aq.).
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