Biomedical Engineering Reference
In-Depth Information
SCHEME 7.26
Transformation of furan precursors into three diverse scaffolds. Reagents and
conditions: (i) NBS, NaHCO
3
, NaOAc, THF/H
2
O (4 : 1), rt, 1 h; (ii) PPTS, DCM, 40
◦
C, 20 h.
SCHEME 7.27
Conversion of 2-vinylbenzamides to fused isoindolinones. Reagents and
conditions: (i) OsO
4
/NaIO
4
/DABCO, THF/H
2
O (1 : 1); (ii) 50% TFA/DCM; (iii) 0.1 M
NaOH (aq.).