Biomedical Engineering Reference
In-Depth Information
TABLE 5.17 3-Azatricyclo[5.1.1.0]nonanes 73 Obtained in the Reaction Sequence
Shown in Scheme 5.28
Entry
70
71
Product, Yield (%)
1
70a
71a
73a ,80
2
70a
71b
73b ,95
3
70a
71c
73c ,55
4
70b
71a
73d ,68
5
70b
71b
73e ,84
6
70b
71c
73f ,76
7
70c
71a
73g ,84
8
70c
71b
73h ,57
9
70c
71c
73i ,71
10
70d
71a
73j ,75
11
70d
71b
73k ,72
12
70d
71c
73l ,70
13
70e
71a
73m ,69
14
70e
71b
73n ,79
15
70e
71c
73o ,74
SCHEME 5.29 Preparation of a tricyclic amine library.
 
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