Biomedical Engineering Reference
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TABLE 5.10 Representative Set of 1,4-Benzoxazines 35 Demonstrating the Scope with
o -Aminophenols (R = H, Me) a
Entry
Substrate
Product
Yield (%) b
1
35i ,56
2
35j ,60
3
35k ,65
4
35l ,26
5
35m ,10
a Reaction conditions: ( 30 red )
=
2 mM, enamine 34
=
10 mM, MeOH, rt, Pt anode ( E
=+
450 mV vs.
SCE), 4 h; 1 equiv of morpholine was added to the reaction to produce 30 ox .
b Isolated yields.
 
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