Biomedical Engineering Reference
In-Depth Information
SCHEME 3.23
Silver (I)-promoted [3
+
2] cycloaddition reaction of azomethine ylides with
unactivated alkenes to generate highly reactive pyrrolidine intermediates.
SCHEME 3.24
Homopropargylic alcohols are generated through a three-component reac-
tion of enantioenriched allenylsilanes, aldehydes, and silyl ethers. When a pendant azide is
present, an intramolecular [3
+
2] cycloaddition reaction occurs to generate bi- and tricyclic
compounds.
