Biomedical Engineering Reference
In-Depth Information
complex traits such as energy capture and conversion, environmental stress
adaptation and product profiles. Those systems that demonstrate not only prom-
ising phenotypes but superior features as a genomics research model, such as
certain Nannochloropsis, Chlorella and Phaeodactylum strains, are emerging as
promising research models for the functional genomics of oleaginous microalgae.
Due to their rich genomic resources, compact genomes, relatively simple gene
structures, wide ecological adaptation, and rich collections of natural strains,
together with their demonstrated capability for outdoor open-pond photosynthetic
cultivation, organisms such as Nannochloropsis spp. and Chlorella spp. can serve
as research models and production strains for robust, scalable and economical
production of fuels and chemicals. Integrated technology development that
supports the complete chain of microalgal production systems, including micro-
algae phylogeny, physiology, genetics, systems biology, metabolic engineering,
pathogenesis, field cultivation, bioprocess engineering, biorefinery, and techno-
economical
analysis,
should
enable
concrete
progresses
towards
the
era
of
photosynthetic biofuels.
Acknowledgments We apologize to the many researchers whose past and ongoing works
contributed to the development of microalgal energy in China but were not cited in this brief
review.
References
1. NBSC
(2010)
Statistic
yearbook
of
China
(National
Bureau
of
Statistics
of
China).
http://wwwstatsgovcn/tjsj/ndsj/2010/indexchhtm
B
eijing China
2. Li YG, Xu L, Huang YM, Wang F, Guo C, et al (2011) Microalgal biodiesel in China:
opportunities and challenges. Appl Ener
3. Wijffels RH, Barbosa MJ (2010) An outlook on microalgal biofuels. Science 329:796
4. Hu Q, Sommerfeld M, Jarvis E, Ghirardi M, Posewitz M et al (2008) Microalgal
triacylglycerols as feedstocks for biofuel production: perspectives and advances. Plant J
54:621-639
5. Chisti Y (2007) Biodiesel from microalgae. Biotechnol Adv 25:294-306
6. Sheehan J (1998) A look back at the US Department of Energy's aquatic species program:
biodiesel from algae: National Renewable Energy Laboratory Golden, CO
7. Dunahay TG, Jarvis EE, Dais SS, Roessler PG (1996) Manipulation of microalgal lipid
production using genetic engineering. Appl Biochem Biotechnol 57:223-231
8. Dunahay
TG,
Jarvis
EE,
Roessler
PG
(1995)
Genetic
transformation
of
the
diatoms
Cyclotella cryptica and Navicula saprophila. J Phycol 31:1004-1012
9. Roessler PG, Bleibaum JL, Thompson GA, Ohlrogge JB (1994) Characteristics of the gene
that encodes acetyl CoA carboxylase in the diatom Cyclotella crypticaa. Ann NY Acad Sci
721:250-256
10. Roessler P, Ohlrogge J (1993) Cloning and characterization of the gene that encodes acetyl-
coenzyme A carboxylase in the alga Cyclotella cryptica. J Biol Chem 268:19254
11. Li Y, Han D, Hu G, Dauvillee D, Sommerfeld M et al (2010) Chlamydomonas starchless
mutant defective in ADP-glucose pyrophosphorylase hyper-accumulates
triacylglycerol.
Metab Eng 12:387-391
12. Leon-Banares
R,
Gonzalez-Ballester
D,
Galvan
A,
Fernandez
E
(2004)
Transgenic
microalgae as green cell-factories. Trends Biotechnol 22:45-52
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