Biomedical Engineering Reference
In-Depth Information
1.2
25 h
Steady state
1.0
0.8
0.6
20 h
0.4
15 h
0.2
with binding
without binding
10 h
5 h
0.0
0
0.2
0.4
0.6
0.8
1
Radial distance from the center of cartilage (mm)
FIGURE 11.8
Free solute uptake ratio ( R f ) as a function of radial distance from center of
cartilage undergoing free diffusion, with or without consideration of binding
effects ( c I 0 = 40 nM). Time between each curve is 5 h.
40
30
20
0.1 Hz at 2% strain
0.01 Hz at 2% strain
10
10
0
1
2
3
4
5
Time (h)
FIGURE 11.9
Percent increase in average total IGF-I uptake ratio ( R u ), as a function of
time, at 2% peak-to-peak strain amplitude and various frequencies ( c I 0
=
40 nM).
 
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