Biomedical Engineering Reference
In-Depth Information
(a)
(b)
Figure 2.16.
SEM images showing macroporosity (A) and microporosity (B) in sintered cow
bone.
Medical and dental applications of calcium phosphate biomaterials include:
repair of bone defects, bone fracture repair, alveolar ridge augmentation, ear im-
plants, spine fusion, etc. (Table 2.6) HA has been demonstrated to be an effi cient
carrier for bone growth factors [53] or for drug delivery [23]. More recently,
synthetic bone mineral was demonstrated to prevent bone loss induced either by
mineral defi ciency or estrogen defi ciency in rats [85,105].
ACKNOWLEDGMENTS
Support of research grants from the National Institutes of Health for some of the
author's work presented here are gratefully acknowledged. Special thanks to
Gary Cantig and Fang Yao for the preparation of some of the fi gures included in
this chapter.
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