Biomedical Engineering Reference
In-Depth Information
14
DESIGN OF
SUPERMACROPOROUS
BIOMATERIALS VIA GELATION
AT SUBZERO TEMPERATURES—
CRYOGELATION
Fatima M. Plieva
1,2
, Ashok Kumar
3
, Igor Yu. Galaev
1
,
and Bo Mattiasson
1
1
Department of Biotechnology, Lund University, SE-22100 Lund, Sweden
2
Protista Biotechnology AB, SE-22370 Lund, Sweden
3
Department of Biological Sciences and Bioengineering, Indian Institute of
Technology Kanpur, Kanpur, India
Contents
14.1 Overview
500
14.2 Introduction
500
14.3 Preparation of Supermacroporous Biomaterials through
Cryogelation Technique
502
14.3.1 General Concept of Cryogelation
502
14.3.2 Parameters Infl uencing Cryostructuration (Cryogelation) of
Polymeric Systems
504
14.3.2.1 Freezing Rate and Freezing Temperature
504
14.3.2.2 Concentration and Composition of Gel Precursors in the
Initial Reaction Mixture
508
14.4 Preparation of Macroporous Gels (MGs) from Different Gel Precursors
513
14.4.1 Physically Cross - Linked MGs
513
14.4.2 Covalently Cross - Linked MGs
515
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