Biomedical Engineering Reference
In-Depth Information
techniques (especially micro/nanometer scale processing) may play an important
role in the development of next-generation biomaterials with the potential to
interact with cells at cellular, as well as sub-cellular, scales.
8.6 BRIEF OVERVIEW OF CHAPTERS IN THE SECTION
ON PROCESSING
Following this introductory chapter, this section on processing consists of
chapters that describe some emerging manufacturing techniques such as Laser
Assisted Net Shaping (LENS) as well as processing involved in designing bioma-
terials for applications such as bioactive scaffolds and polymeric drug delivery
systems.
The chapter written by R. Banerjee (University of North Texas, U.S.)
demonstrates how novel near-net shape processing technologies, such as laser-
engineered net shaping (LENS
TM
) can be utilized to rapidly manufacture
custom - designed functionally - graded unitized implants with site - specifi c proper-
ties. The chapter also discusses the mechanical properties, the electrochemical
response, wear resistance and biocompatibility of laser-deposited beta Ti alloys
and metal-matrix composites for orthopedic applications.
After reviewing the present status of the development of bioinert ceramics
for Total HIP joint Replacement (THR), the chapter by Omer Van Der Biest
(Katholieke Universiteit Leuven, Belgium) and his co-workers, largely focuses on
the design principles of Electrophoretic deposition as a novel processing route to
develop functionally gradient materials (FGM) based on biocompatible ceramics.
The processing issues to select optimal parameters to obtain gradient in composi-
tion and properties for small-to-large scale ZrO
2
/Al
2
O
3
based implant materials
are discussed.
In the chapter written by Pio González (Universidade de Vigo, Lagoas-
Marcosende, Vigo, Spain) and co-workers, bioinspired ceramics for bone tissue
replacement are discussed. The chapter focuses on biomorphic silicon carbide
ceramics fabricated from bio-derived cellulose templates that can be applied as
scaffolds for bone substitution because of their lightweight, high-strength and
interesting biocompatibility with natural tissues. The chapter discusses the micro-
structure, chemical composition, and mechanical properties of different types of
biomorphic silicon carbide ceramics along with the
in vitro
biocompatibility test
data.
The chapter by Artemis Stamboulis (University of Birmingham, Birming-
ham, UK) and co-workers discusses the design and characterization of ionomeric
glasses with a focus on the crystallization aspects of the glasses.
The chapter by Dhirendra Katti (Indian Institute of Technology, Kanpur,
India) and co-workers describes the processing of polymeric systems for the syn-
thesis of nanofi bers that are to be used as scaffolding systems for tissue engineer-
ing applications. The chapter emphasizes electrospinning techniques and discusses
the various polymeric systems that have been used to generate nanofi bers which
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