Biomedical Engineering Reference
In-Depth Information
Air bubble
detector
Centrifugal
pump
Add
volume
Air removal
Volume
buffer
Venous
bubble
trap
Electronic
venous line
occluder
Remove
volume
AutoVent TM
arterial
filter
Oxygenator
6.4 Schematic representation of novel minimized circuit with air
handling characteristics.
￿ ￿ ￿ ￿ ￿
6.5 Heart-lung machine operating with minimized circuitry.
6.5.3 Leukocyte fi ltration
Activation of leukocytes and their mobilization towards injured tissues are
critical steps in infl ammation and reperfusion injury. Activated neutrophils
may exert damaging effects on tissues of the host, indirectly by releasing
infl ammatory mediators and directly by damaging endothelial cells with
proteolytic enzymes.
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