Biomedical Engineering Reference
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Table 2.3 Representative hard corona proteins associated with AuNRs incubated in 100 % FBS
for different thermal and photothermal treatments (incubation at 37, 45 C, and continuous lasers),
as identified by LC-MS/MS; standard deviations were obtained from three individual tests
(adapted with permission from [ 34 ])
NSpC
Molecular
weight
(kDa)
Continuous
laser
(27.5 min)
Continuous
laser
(55 min)
Heated
at 45 C
37 C
Protein name
69
Serum albumin
7.72 3.10
6.69 1.50
9.12 3.05
6.57 1.58
46
α
-1-
antiproteinase
precursor
5.6
1.49
4.76
0.93
4.07
0.33
4.82
0.64
38
α
-2-HS-
glycopro-
tein precursor
14.58
1.22
6.13
0.05
11.06
3.01
11.16
1.39
30
Apolipoprotein
A-I precursor
4.15
0.91
8.37
1.96
3.58
0.98
4.21
0.02
16
Hemoglobin fetal
subunit beta
16.65
7.04
9.81
1.79
12.31
2.96
9.66
2.44
15
Hemoglobin
7.55
0.70
14.14
4.91
4.78
0.72
3.71
0.70
11
Apolipoprotein
A-II precursor
20.95
1.46
3.92
0.57
5.52
0.05
6.01
1.01
11
Apolipoprotein
C-III
precursor
0.52
0.57
3.12
0.75
2.27
1.18
1.88
0.79
Fig. 2.9 Scheme showing the selective entrance of serum albumin in the composition of protein
corona of the laser-activated gold nanorods (adapted with permission from [ 34 ])
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