Biomedical Engineering Reference
In-Depth Information
Fig. 16.6
(
a
)SEMof
longitudinal CG scaffold
section displaying aligned,
elongated pore structure. Scale
bar: 100
m
m. (
b
)SEMof
transverse CG scaffold section
displaying round, isotropic
pore structure. Scale bar:
100
m
m. (
c
) SEM of scaffold-
membrane interface showing
integration of two materials.
Scale bar: 1 mm. (Reproduced,
with permission, from Caliari
et al. [
1
])
(data not shown). Mechanically, membranes are isotropic in plane and both physical
(dehydrothermal: DHT) and chemical (1-ethyl-3-[3-dimethylaminopropyl]
carbodiimide hydrochloride: EDAC) crosslinking methods can be used to further
crosslink the membranes [
1
]. As expected, significantly crosslinking was
introduced via EDAC treatment. Notably, the highest crosslinked CG membrane
displayed ~7-10-fold increases in modulus over non-crosslinked controls [
1
],
comparable to increases seen for CG scaffolds treated with the same crosslinking
strategies [
57
].
Search WWH ::
Custom Search