Synthesis of Layered, Graded Bioscaffolds - Structural Interfaces and Attachments in Biology - page 346

Fig. 16.4 Top : Stress-strain curves of CG, CGCaP, and CG-CGCaP ( T f ¼ 10 C) scaffolds,
each demonstrating the distinct linear, collapse plateau, and densification regimes characteristic
of low density open-cell foams. Bottom : Ultrasound elastography images, corresponding to
applied strains of 0.0, 0.3, and 0.6, illustrate the local strain experienced in the CG-CGCaP
scaffold
Further, the elastic modulus of the individual struts that define the scaffold network
has also been characterized [ 57 ]; scaffold modulus has also been shown to remain
consistent in orthogonal planes of isotropic scaffolds [ 57 ], but vary significantly
between orthogonal planes of anisotropic scaffold variants [ 53 ]. The mechanical
behavior of CGCaP scaffolds under compression as well as the modulus of the
individual mineralized struts have also been evaluated [ 41 , 46 ]. These results offer
insight to the mechanical properties of a standardized set of CG materials. For the
model multi-compartment scaffold, the CG compartment exhibited a modulus of
9 1 kPa, while the CGCaP compartment possessed a modulus of 155 17 kPa.