Biomedical Engineering Reference
In-Depth Information
Fig. 5.30 In vivo gluteal tissue compound force-relaxation curves a force-time, b force-
displacement obtained at a constant ramp speed of 0.68 mms
-1
and various ramp displacements,
and c normalized (by the time at peak force and the peak force) filtered experimental force-time
responses from experimental data provided in Fig.
5.30
a
5.2.4.2 Relaxation Experiments
The employed test devices, protocols including indentation locations and MR-
settings of relaxation testing are similar to the protocols applied for long-term
material parameter evaluation as described in
Sect. 5.2.2
.
Stepwise Indentation Procedure: In the first step, long-term elastic tissue
material parameters were established analogue to the procedure described in
Sects.
5.2.2
and
5.2.3
. Stepwise and cyclic tissue indentation with holding periods was
performed at a constant loading and unloading speed to separate the elastic from
the inelastic tissue material properties.
Relaxation Experiments: After long-term material parameter evaluation,
displacement-controlled ramp-and-hold indentation testing at the buttocks was
performed. Using the MR-compatible loading device (cf. Fig.
5.13
a), separate
tissue indentation with a maximum ramp displacement of 10-, 20-, 30-, 40 mm at a
constant ramp speed of 0
:
68 mm s
1
(equivalent to an (engineering) strain rate of
0
:
75 % s
1
along the indenter axis) followed by a hold phase of 180 s was per-
formed. Corresponding tissue deformation after each ramp phase was MR-scanned,
Fig.
5.29
. Indenter force and displacement were recorded with a time resolution of
0.05 s. The recorded force-time relation at 40 mm ramp displacement together
with the MR-scanned individually deformed tissue geometries after the ramps
served as constraints in the parameter optimization process.
Force-Time-Data: Between the indentation tests, a 20 min pause was introduced
to allow for tissue regeneration (shown to be sufficient since the single ramp phases of
all tests coincided, cf. Fig.
5.30
a). Resulting tissue force-time and force-displacement
responses are depicted in Fig.
5.30
a and b. Significant force-relaxation occurred
during ramp displacement and at constant indenter displacement after the ramp,