Biomedical Engineering Reference
In-Depth Information
6
General Strategy for FMC Experiments
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7
Concluding Remarks
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8
References
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List of Symbols and Abbreviations
A
Total area of immobilized enzyme particles
c
S
,c
P
Particle substrate and product concentration,respectively
c
Sb
,c
Pb
Bulk phase substrate and product concentration,respectively
C
P
Specific heat capacity of liquid phase
D
S
,D
P
Effective diffusion coefficient of substrate and product,respectively
D
H
r
Molar reaction enthalpy
k
1
First order rate constant
K
m
Michaelis constant
K
i
Inhibition constant
P
Parameter in Eq. (29)
P
Vector of kinetic parameters
r
Particle radial coordinate
R
Particle radius
T
Absolute temperature
D
T
r
Temperature difference between column input and output
v
0
Initial reaction time
v
kin
Kinetic reaction rate corresponding to insignificant mass transfer
limitation
v
obs
Observed reaction rate
V
C
Total bed volume in column
V
L
Bed void volume in column
V
m
Maximum reaction rate
V
p
Total particle volume in column
V
T
Total liquid volume in recirculation system
w
Superficial flow rate
z
Axial coordinate
Z
Length of packed bed
a
Transformation parameter defined by Eq. (18)
e
Bed void fraction
F
Thiele modulus
h
Effectiveness factor
r
Fluid density
Con A
Concanavalin A
CPG
Controlled pore glass
ELISA
Enzyme-linked immunoassay
FMC
Flow microcalorimetry
IMB
Immobilized biocatalyst
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