Bioactive Agents from Natural Sources: Trends in Discovery and Application - Advances in Biochemical Engineering Biotechnology - page 109

Fig. 2. Inhibition of cholesterol biosynthesis by lovastatin and its analogs
mic drugs instead of encouraging better nutrition.However,HMG-CoA reduc-
tase inhibitors seem to be extremely helpful therapeutics for patients suffering
from hereditary hyperlipidemia causing severe coronary heart diseases, and
cardiac infarction of even very young people.
2.4
Antidiabetic Drugs
Acarbose was discovered in a target-directed screening from the culture broth of
a neglected genera of actinomycetes called Actinoplanes spec. by researchers at