Wound Healing: Multi-Scale Modeling - Multiscale Computer Modeling in Biomechanics and Biomedical Engineering - page 327

Fig. 3 Snapshots at consecutive times of a cell engulfing bacteria

Table 1 Values for the
various parameters used

Parameter Value Unit

mm 4 /h/mol b 5

c 1

mol/mm 3 /h

0 : 01

mm 6 /h

4p

mm 2 /h D

a 1 : 5 1/h

2.2 The Colony Scale

To make the present manuscript as self-contained as possible, we repeat some of
the equations presented in Vermolen and Gefen [ 1 ]. Presently, we are also
extending the model to simulate infected cell colonies. To this extent, we consider
a flat substrate on which cells are allowed to move. The projection of the cells onto
the substrate is assumed to be circular. Upon moving, each cell exerts a traction