Biomedical Engineering Reference
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Fig. 2 Construction of a multi-level model of a bio-artificial muscle (BAM). In every integration
point of the macroscopic mesh an RVE is defined representing the microstructure. Micro model A
represents a typical microstructure expected in a BAM. Micro model B represents the cross
section of a mature muscle (adapted from Breuls [ 12 ])
Fig. 3 Results of a simulation with microstructure A. The deformed macroscopic geometry
(centre) is shown, surrounded with four selected RVEs. The color bar next to the macroscopic
mesh represents the macroscopic SED (in N/m 2 ). The color scale bars next to the RVEs represent
the SED, averaged over the cell area (Adapted from: Breuls [ 12 ])
integration point, the same RVE was defined. Both cells as well as ECM were
modelled as elastic materials, using a Neo-Hookean material model. At x = 0 and
y = 0, displacements were suppressed in y- and x-direction, respectively. To
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