Biomedical Engineering Reference
In-Depth Information
Chapter 45
CUSTOMIZED NANOCOMPOSITE
LASER SINTERING FOR BONE TISSUE
ENGINEERING
Bin Duan and Min Wang
*
Department of Mechanical Engineering, Faculty of Engineering,
the University of Hong Kong, Pokfulam Road, Hong Kong
*memwang@hku.hk
In scaffold-based tissue engineering, controlling the macro- and
micro-architecture of a scaffold and fulfilling a customized scaf-
fold design with a complex anatomic shape are of great impor-
tance for the clinical success of a tissue engineering strategy.
In order to achieve extensive and detailed control over scaf-
fold architecture, solid free-form fabrication (SFF), also called
“rapid prototyping (RP) technologies”, is introduced into the
tissue engineering field and have been developed for scaffold pro-
duction. This chapter presents our investigations into the fab-
rication of three-dimensional (3D) calcium phosphate (Ca-P)/
poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) nanocompos-
ite scaffolds through the use of selective laser sintering (SLS).
A new strategy of using nanocomposite microspheres instead
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