Biomedical Engineering Reference
In-Depth Information
A. Doubling timing of different MSCs
120.0
hfB MSC
haB MSC
hUC MSC
hAT MSC
100.0
80.0
60.0
40.0
20.0
0.0
different MSCs
90
80
70
60
50
hfB MSC
haB MSC
hUC MSC
hAT MSC
40
30
20
10
0
different MSCs
Figure 43.16a. Doubling time and CFUs of different MSCs. See also Color
Insert.
immunogenicity than haMSCs. 58 , 59 In conclusion, because of their
great proliferative capacity, high osteogenic potential both in vitro
and in vivo ,andlowimmunogenicity,hfMSCscanbeapromisingcel-
lular source for BTE applications.
A challenging issue for the clinical translation of cell-based
scaffold constructs is the maintenance of viability and proper
 
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