Biomedical Engineering Reference
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Figure 43.15c.
H&E staining evaluation of specimen at 12 weeks after
implantation.Group1wasnotimplantedwithanykindoffibrin/humanBM
stem cells (sham operation). Group 2 was implanted with a fibrin glue scaf-
fold in the defect region. Group 3 was implanted with a fibrin/human BM
stem cells composite scaffold in the defect region.
strategies. The ideal cellular source for a cell-based BTE approach
should include the following characteristics: (1) no or low immuno-
genicity, (2) no tumorigenicity, (3) immediate availability, (4) avail-
ability in pertinent quantities, (5) a rapid cell proliferation rate, (6)
apredictableandconsistentosteogenicpotential,and(7)controlled
integration into the surrounding tissues.
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