Biomedical Engineering Reference
In-Depth Information
40.4 Conclusions and Outlook
Thisarticlehasfocusedalmostontheuseofbiodegradablescaffolds
asthegraftmaterialforeffectiveboneregenerationappliedbytissue
engineering and the regenerative medicine concept.
5
The result
showedthattheywouldbeusefulasascaffoldforboneregeneration
and could be used in clinical application. The application is
successful, and these cases would be observed and maintained in
the future.
Moreover, the technology would reduce the patient burden and
provide minimally invasive cell therapy for patients. It might be a
clinical alternative to autogenous bone grafts, which are associated
withattendant donorsite morbidity.
17
-
20
Acknowledgments
TheauthorswishtothankDrs.MinoruUeda,JaeSeongBoo,Ryotaro
Ozawa, Kenji Ito, Sayaka Nakamura, Ryoko Yoshimi, Kenji Hara, and
Eri Umemura, members of the Department of Oral and Maxillofacial
Surgery, Nagoya University Graduate School of Medicine, and
Shuguang Zhang of the Center for Biomedical Engineering at
Massachusetts Institute of Technology for their assistance and
contributions to this study. We also thank ArBlast Co. Ltd., Kobe,
Japan,and3DMatrixCo.Ltd.,Tokyo,Japan,fortheirhelp.Thiswork
was supported in part by Grants-in-Aid for Scientific Research (No.
20659297, 21390507) from the Japan Society for the Promotion of
Science.
References
1. U. Bilkay, M. Alper, N. Celik, O. Erdem, H. Kerem, C. Ozek, O. Zekioglu, Y.
Delen, E. Songur, and A. Cagdas.
J. Craniofac. Surg.
,
585
(2004).
2. H. Yoshimoto, Y. M. Shin, H. Terai, and J. P. Vacanti.
Biomaterials
,
2077
(2003).
3. W.-J. Li, C. T. Laurencin, E. J. Caterson, R. S. Tuan, and F. K. Ko.
J. Biomed.
Mater. Res.
,
613
(2002).
4. R. H. Hardy, R. Kania, S. Verliac, A. Lortat-Jacob, and J. Benoit.
Eur. J.
Orthop. Surg. Traumatol
.,
63
(1997).
Search WWH ::
Custom Search