BIODEGRADABLE SCAFFOLDS FOR BONE REGENERATION - Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine - page 826

Figure 40.6. Histological evaluation of PRP, PCBM, and TEB (MSCs/PRP)
implantations at each time point. 18 Bone defects were prepared with a
trephine bar. Sections of representative implants are shown from each
group. The sections were stained with hematoxylin & eosin. Original
magnification 40) for all photographs. (A) 2 weeks

PRP group, (B) 4 weeks PRP group, (C) 8 weeks PRP group, (D) 2 weeks
PCBMgroup,(E)4weeksPCBMgroup,(F)8weeksPCBMgroup,(G)2weeks
TEB group, (H) 4 weeks TEB group, and (I) 8 weeks TEB group. See also
Color Insert.

× 200 (inner square, ×

40.3 Clinical Application

40.3.1 Preparation and Clinical Application of MSCs, PRP,
and Injectable TEB
MSCs were isolated from the patients and incubated according to
the reported method (Fig. 40.7A). 19 , 20 , 25 In cultures, MSCs were
trypsinized and used forclinical treatment.